The Genomics Core provides a centralized resource for access to cutting-edge equipment used in DNA sequence and transcript analysis. 

The Genomics Core is committed to delivering high-quality services with fast turnaround times. Its well-trained staff is available to consult with users on how to best utilize its offerings. 

The core continually assesses and improves its services to ensure it remains at the forefront of the field. Additionally, the core introduces new services as needed to meet the requirements of investigators at Holden Comprehensive Cancer Center.

Services provided include:

• Genome Sequencing
  • Element AVITI24 & Illumina short-read sequencers, Oxford Nanopore long-read sequencing systems (PromethION 2, MinION and Flongle), 2 Revvity Sciclone liquid handling systems, Eppendorf epMotion liquid handling system, Covaris E220 sonicator
• Single-Cell & Spatial Omics Analysis
  • 10X Genomics Chromium X and iX single cell controllers, LUNA-FL cell counter, 10X Genomics Visium CytAssist
• Sanger Sequencing
  • Applied Biosystems (ABI) 3730xl DNA sequencer, Revvity Zephyr liquid handling system, 6 ABI thermocyclers
• DNA Microarray
  • Illumina iScan BeadArray System
• Oligonucleotides
• Nucleic Acid Quality Assessment
  • 2 Agilent Bioanalyzers, 2 Agilent TapeStations, Trinean DropSense 16, NanoDrop spectrophotometer, Qubit Fluorometer, and Agilent Fragment Analyzer & Femto Pulse systems
• Quantitative DNA/RNA Analysis
  • ABI QuantStudio 7 Flex and QuantStudio 7 Pro sequence detection systems, Bio-Rad QX200 Droplet Digital PCR system, and NanoString nCounter FLEX system